BCL6 PROTAC 15 ( —— )

Catalog No. M16949 CAS No.

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Datasheet

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Product Name

BCL6 PROTAC 15
Note

Research use only, not for human use.
Brief Description

BCL6 PROTAC 15 is a novel B-cell lymphoma 6 (BCL6) PROTAC, significantly degrade BCL6 in a number of DLBCL cell lines.
Description

BCL6 PROTAC 15 is a novel B-cell lymphoma 6 (BCL6) PROTAC, significantly degrade BCL6 in a number of DLBCL cell lines, but neither BCL6 inhibition nor degradation selectively induces marked phenotypic response.
Synonyms

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Pathway

PROTACs
Target

PROTAC
Recptor

PROTAC
Research Area

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Indication

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CAS Number

--
Formula Weight

976.48
Molecular Formula

C47H58ClN9O12
Purity

>98% (HPLC)
Solubility

——
SMILES

——
Chemical Name

4-((R)-25-chloro-41-methyl-42-oxo-41,42,43,44-tetrahydro-5,8-dioxa-3-aza-4(6,8)-quinolina-2(2,4)-pyrimidina-1(1,2)-piperazinacyclononaphane-14-yl)-N-(3-(2-(2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)ethoxy)ethoxy)propyl)-4-oxobutanamide compound with ethane (1:1)

1. McCoull W, et al. ACS Chem Biol. 2018 Oct 17. doi: 10.1021/acschembio.8b00698.

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